CRUK Bioinformatics Summer School 2017

24th - 28th July 2017

Analysis of Cancer Genomes


High-throughput technologies such as next generation sequencing (NGS) can routinely produce massive amounts of data. These technologies allow us to describe all variants in a genome and international collaborative efforts such as The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) have begun to catalogue and release data on genomic variation in a variety of cancer types.

However, such datasets pose new challenges in the way the data have to be analyzed, annotated and interpreted which are not trivial and are daunting to the wet-lab biologist. This course covers state-of-the-art and best-practice tools for the analysis of cancer genomes. We describe, and give hands-on experience of, the entire analysis workflow from raw data generated by a sequencing machine to deriving variant calls (SNVs, copy-number and structural variants) that are ready for downstream analysis and interpretation


Enthusiastic and motivated wet-lab biologists who want to gain more of an understanding of NGS data and eventually progress to analysing their own data


The course will include a great deal of hands-on work in R and at the command line. In order for you to make the most of the course we strongly recommend that you take an introductory course, or have sufficient experience in the following areas:-

More specific requirements and references can be found here (


(all Cancer Research Uk Cambridge Institute)





If required, free bed and breakfast accommodation will be provided for attendees in Downing College - close to the course’s location. Please let us know on the registration form if you need accommodation and when you plan to check-in and check-out. Please note that the course ends at 13:30 on Friday 28 July and accommodation is not provided for Friday night.


Day Zero 18:00 - ..

Day One 09:30 - 17:00

Day Two 09:30 - 17:00

Day Three 09:30 - 17:00

Day Four 09:30 - 17:00

Day Five (1/2 day) 09:30 - 12:30

Social Events