March 2019

HTS Applications - Overview

DNA Sequencing

  • Genome Assembly

  • SNPs/SVs/CNVs

  • DNA methylation

  • DNA-protein interactions (ChIPseq)

  • Chromatin Modification (ATAC-seq/ChIPseq)

RNA Sequencing

  • Transcriptome Assembly

  • Differential Gene Expression

  • Fusion Genes

  • Splice variants

Single-Cell

  • RNA/DNA

  • Low-level RNA/DNA detection

  • Cell-type classification

  • Dissection of heterogenous cell populations

RNAseq Workflow

Library Preparation

Library Preparation

Bioinformatics Analysis